Monthly Research Highlights

NOVEMBER 2013

Dr. Torres is recognized by The American Society for Microbiology’s Committee on Microbiological Issues Impacting Minorities for outstanding contributions to the field of microbiology.

Staphylococcus aureus Leukotoxin ED Targets the Chemokine Receptors CXCR1 and CXCR2 to Kill Leukocytes and Promote Infection.

Nature Reviews Microbiology-Research Highlights: CXCRs mark the spot.

Dr. Victor Torres Lab

 

AUGUST 2013

The B55 alpha regulatory subunit of Protein Phosphatase 2A mediates FGF-induced p107 dephosphorylation and growth arrest in chondrocytes.

Dr. Claudio Basilico's Lab

JUNE 2013

Sox2 regulates YAP1 to maintain stemness and determine cell fate in the osteo-adipo lineage.

Dr. Claudio Basilico's Lab

Staphylococcus aureus LukAB cytotoxin kills human neutrophils by targeting the CD11b subunit of the integrin Mac-1.
 
Dr. Victor Torres Lab
 

APRIL 2013

Worm therapy: Why parasites may be good for you.

Dr. P'ng Loke's Lab

 

Spotlight Section: Articles of Significant Interest Selected by the Infection and Immunity Editors “Leukocidin AB Facilitates the Escape of Staphylococcus aureus after Engulfment by Human Neutrophils”

“Staphylococcus aureus elaborates the leukocidin AB to mediate escape from within human neutrophils”.

Dr. Victor Torres Lab

 

JANUARY 2013

CCR5 is a receptor for Staphylococcus aureus leukotoxin ED

Faculty of 1000: Recommended as being of special significance in its field by Rino Rappuoli and Fabio Bagnoli 

A surprising link between a staph toxin and CCR5

Dr. Victor Torres Lab and Dr. Derya Unutmaz Lab

 

DECEMBER 2012

Population structuring of multi-copy, antigen-encoding genes in Plasmodium falciparum

Mathematical models and empirical data show that immune selection structures the parasite population into “ var strains”
eLIFE Insight commentary “ Mathematics and Malaria”
Karen Day with modeling collaborators Yael Artzy and Mercedes Pascual (HHMI Univ Michigan)

Dr. Karen Day Lab

 

A Drug Used to Treat HIV Might Defuse Deadly Staph Infections
 
Dr. Victor Torres Lab and Dr. Derya Unutmaz Lab
 

JULY 2012

Overexpression of cyclin E/CDK2 complexes overcomes FGF-induced cell cycle arrest in the presence of hypophosphorylated Rb proteins.

Dr. Claudio Basilico's Lab

Control of viral latency in neurons by axonal mTOR signaling and the 4E-BP translation repressor.

Editors' Choice Virology: Connecting Stress to Viral Reactivation by Annalisa M. VanHook Sci.

Dr. Ian Mohr Lab and Dr. Angus Wilson Lab

 

DECEMBER 2011

FtsH-dependent degradation of phage shock protein C in Yersinia enterocolitica and Escherichia coli

Universally conserved membrane protease in prokaryotes degrades phage shock protein C in Y. enterocolitica and E. coli

Dr. Andrew Darwin Lab

 

Staphylococcus aureus leukocidin ED contributes to systemic infection by targeting neutrophils and promoting bacterial growth in vivo

Microbe Hunters Place Staph in the Crosshairs

Dr. Victor Torres Lab

 

An RNA Pyrophosphohydrolase Triggers 5'-Exonucleolytic Degradation of mRNA in Bacillus subtilis

Dr. Joel Belasco Lab

 

The Yersinia enterocolitica Phage-shock-proteins B and C can form Homodimers and Heterodimers in vivo with the Possibility of Close Association between Multiple Domains

Dr. Andrew Darwin Lab